Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Applications for TSC22/TSC22D1 Antibody (OTI4H8) [DyLight 350]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TSC22

Transforming growth factor-beta-stimulated clone-22 (TSC-22) acts as a transcriptionalregulator to modulate cell growth and differentiation and cell death. TSC-22 contains a leucine zipper domain as well as a nuclear export signal, resulting in cytoplasmic localization in living cells. However, concomitant with the induction of apoptosis, TSC-22 translocates from the cytoplasm to the nucleus and shows transcriptional regulatory activity. TSC-22 acts as a major downstream component in the TGF-beta pathway, and also the PPARgamma signalling pathway. The association of these two pathways with tumor suppression, and the significant downregulation of TSC-22 mRNA in various cancer types, such as brain and salivary gland tumors, imply an antiproliferative role for TSC-22.

Long Name

TSC22 Domain Family, Member 1

Alternate Names

Egr5, TGFB1I4, TSC22D1

Gene Symbol

TSC22D1

Additional TSC22 Products

Product Documents for TSC22/TSC22D1 Antibody (OTI4H8) [DyLight 350]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for TSC22/TSC22D1 Antibody (OTI4H8) [DyLight 350]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

Spectra Viewer
Flow Cytometry

TSC22/TSC22D1 Antibody (OTI4H8) [DyLight 350]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-74654UV

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all TSC22 Antibodies »

Product Specifications

Immunogen

Reactivity Notes

Clonality

Host

Isotype

Applications for TSC22/TSC22D1 Antibody (OTI4H8) [DyLight 350]

Flow Cytometry

Immunohistochemistry

Immunohistochemistry-Paraffin

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: TSC22

Long Name

Alternate Names

Gene Symbol

Additional TSC22 Products

Product Documents for TSC22/TSC22D1 Antibody (OTI4H8) [DyLight 350]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for TSC22/TSC22D1 Antibody (OTI4H8) [DyLight 350]

CONTACT INFORMATION

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