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TSG Antibody (6E6)

Novus Biologicals, part of Bio-Techne | Catalog # H00057045-M01

Novus Biologicals, part of Bio-Techne
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H00057045-M01

Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Kappa Clone # 6E6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

TWSG1 (NP_065699, 124 a.a. ~ 223 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. AEELSHHENLVSFLETVNQPHHQNVSVPSNNVHAPYSSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF

Reactivity Notes

Human. Other species not tested.

Specificity

twisted gastrulation homolog 1 (Drosophila)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3 Kappa

Scientific Data Images for TSG Antibody (6E6)

Western Blot: TSG Antibody (6E6) [H00057045-M01]

Western Blot: TSG Antibody (6E6) [H00057045-M01]

Western Blot: TSG Antibody (6E6) [H00057045-M01] - Analysis of TWSG1 expression in transfected 293T cell line by TWSG1 monoclonal antibody (M01), clone 6E6.Lane 1: TWSG1 transfected lysate(25 KDa).Lane 2: Non-transfected lysate.
Sandwich ELISA: TSG Antibody (6E6) [H00057045-M01] - Detection limit for recombinant GST tagged TWSG1 is approximately 0.1ng/ml as a capture antibody.

Applications for TSG Antibody (6E6)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TSG

Twisted Gastrulation Protein 1(TWSG1) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins thereby preventing BMPs from binding to their receptors. It can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex.

Long Name

Twisted Gastrulation Homolog 1 [Drosophila]

Alternate Names

TWSG1

Entrez Gene IDs

57045 (Human)

Gene Symbol

TWSG1

OMIM

605049 (Human)

UniProt

Additional TSG Products

Product Documents for TSG Antibody (6E6)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TSG Antibody (6E6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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