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TSLP Antibody (210H1) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # DDX0804B

Novus Biologicals, part of Bio-Techne
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DDX0804B

Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG2A Clone # 210H1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

TSLP was used as immunogen.

Reactivity Notes

Human

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for TSLP Antibody (210H1) [Biotin]

Western Blot: TSLP Antibody (210H1.04) [Biotin] [DDX0804B] - Analysis of TSLP in 1) transfected 293T and 2) untransfected 293T cells using DDX0804.
ELISA: TSLP Antibody (210H1.04) [Biotin] [DDX0804B] - Capture ELISA using DDX0801 (3 ug/ml) and DDX0804B (4 ug/ml).

Applications for TSLP Antibody (210H1) [Biotin]

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:100-1:2000
Application Notes
Western Blot, ELISA
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

Antibody in PBS and 50% Glycerol

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in the dark. Avoid freeze-thaw cycles.

Background: TSLP

Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. TSLP is a four-helix-bundle cytokine that is expressed mainly by barrier epithelial cells and is a potent activator of several cell types such as myeloid dendritic cells. TSLP is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Amino acid sequence analysis has shown poor homology between human and mouse TSLP although they exhibit similar biological functions and are expressed in similar tissues. Despite its predicted molecular weight, TSLP often migrates at a higher molecular weight in SDS-PAGE. At least two differentially spliced isoforms of TSLP are known to exist.

Long Name

Thymic Stromal Lymphopoietin

Alternate Names

thymic stromal lymphopoietin

Gene Symbol

TSLP

Additional TSLP Products

Product Documents for TSLP Antibody (210H1) [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TSLP Antibody (210H1) [Biotin]

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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