TTC8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-49869

Novus Biologicals, part of Bio-Techne
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NBP1-49869
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all TTC8 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KEVLKQDNTHVE corresponding to internal region according to NP_938051.1, NP_938052.1.

Epitope

KEVLKQDNTHVE - Internal region

Specificity

This antibody is expected to recognize all reported isoforms (NP_653197.2; NP_938051.1; NP_938052.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for TTC8 Antibody

Western Blot: TTC8 Antibody [NBP1-49869]

Western Blot: TTC8 Antibody [NBP1-49869]

Western Blot: TTC8 Antibody [NBP1-49869] - (0.2ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for TTC8 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000

Western Blot

0.2 - 0.6 ug/ml
Application Notes
WB: Approx. 60 kDa band observed in human testis lysates (calculated MW of 58.4 kDa band according to NP_653197.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TTC8

This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.

Alternate Names

Bardet-Biedl syndrome 8 protein, BBS8Bardet-Biedl syndrome type 8, RP51, tetratricopeptide repeat domain 8, tetratricopeptide repeat protein 8, TPR repeat protein 8

Entrez Gene IDs

123016 (Human); 76260 (Mouse); 299246 (Rat)

Gene Symbol

TTC8

UniProt

NP_653197.2 (Human)

Additional TTC8 Products

Product Documents for TTC8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TTC8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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