TWEAK/TNFSF12 Antibody (RO5458640) [DyLight 488]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28340G

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Product Datasheet / COA / SDS

Recombinant Monoclonal Antibody

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP3-28340

Alexa Fluor 350

NBP3-28340AF350

Alexa Fluor 405

NBP3-28340AF405

Alexa Fluor 488

NBP3-28340AF488

Alexa Fluor 532

NBP3-28340AF532

Alexa Fluor 594

NBP3-28340AF594

Alexa Fluor 647

NBP3-28340AF647

Alexa Fluor 700

NBP3-28340AF700

Alexa Fluor 750

NBP3-28340AF750

Allophycocyanin

NBP3-28340APC

Biotin

NBP3-28340B

CoraFluor 1

NBP3-28340CL1

DyLight 350

NBP3-28340UV

DyLight 405

NBP3-28340V

DyLight 550

NBP3-28340R

DyLight 594

NBP3-28340DL594

DyLight 650

NBP3-28340C

DyLight 680

NBP3-28340FR

DyLight 755

NBP3-28340IR

FITC

NBP3-28340F

HRP

NBP3-28340H

Janelia Fluor 525

NBP3-28340JF525

Janelia Fluor 549

NBP3-28340JF549

Janelia Fluor 646

NBP3-28340JF646

Janelia Fluor 669

NBP3-28340JF669

mFluor Violet 450 SE

NBP3-28340MFV450

mFluor Violet 500 SE

NBP3-28340MFV500

mFluor Violet 610 SE

NBP3-28340MFV610

PE

NBP3-28340PE

PerCP

NBP3-28340PCP

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Recombinant Monoclonal Human IgG₁ Clone # RO5458640

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TWEAK/TNFSF12 Antibodies »

Product Specifications

Immunogen

TNFSF12 / TWEAK

Clonality

Monoclonal

Host

Human

Isotype

IgG₁

Applications for TWEAK/TNFSF12 Antibody (RO5458640) [DyLight 488]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TWEAK/TNFSF12

CD266 is a 14 kD transmembrane protein known as TWEAK receptor (TWEAK-R) or fibroblast growth factor inducible 14 (Fn14). It is member 12A of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed at low levels in a variety of tissues, such as heart, placenta, lung, muscle, and pancreas. TWEAK-R binds TWEAK (CD255) and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The engagement of Fn14 can induce cell death and may play a role in inflammation, hepatocyte growth, and liver neoplasia. ITEM-4 antibody reacts with both mouse and human Fn14. It is useful for flow cytometric analysis.

Long Name

TNF-like and Weak Inducer of Apoptosis

Alternate Names

TNFSF12

Gene Symbol

TNFSF12

Additional TWEAK/TNFSF12 Products

Product Documents for TWEAK/TNFSF12 Antibody (RO5458640) [DyLight 488]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for TWEAK/TNFSF12 Antibody (RO5458640) [DyLight 488]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

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