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TYRP1 Antibody (CL4906)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61142

Novus Biologicals, part of Bio-Techne
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NBP2-61142
NBP2-61142-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CL4906

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for TYRP1 Antibody (CL4906)

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence:VCDICTDDLMGSRSNFDSTLISPNSVFSQWRVVCDSLEDYDTLGTLCNSTEDGPIRRNPAGNVARPMVQRLPEPQDVAQCLEVGLFDTPPFYSNSTNSFRNTVEGYSDPTGKYDPAVRSLH

Epitope

LEVGLFDTPPFYSNS

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for TYRP1 Antibody (CL4906)

Western Blot: TYRP1 Antibody (CL4906) [NBP2-61142]

Western Blot: TYRP1 Antibody (CL4906) [NBP2-61142]

Western Blot: TYRP1 Antibody (CL4906) [NBP2-61142] - Western blot analysis in human cell line SK-MEL-30.
Immunocytochemistry/ Immunofluorescence: TYRP1 Antibody (CL4906) [NBP2-61142]

Immunocytochemistry/ Immunofluorescence: TYRP1 Antibody (CL4906) [NBP2-61142]

Immunocytochemistry/Immunofluorescence: TYRP1 Antibody (CL4906) [NBP2-61142] - Staining of SK-MEL-30 cells using the Anti-TYRP1 monoclonal antibody, showing specific staining in the vesicles in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
Immunohistochemistry: TYRP1 Antibody (CL4906) [NBP2-61142]

Immunohistochemistry: TYRP1 Antibody (CL4906) [NBP2-61142]

Immunohistochemistry: TYRP1 Antibody (CL4906) [NBP2-61142] - Staining of human tonsil shows no positivity in lymphoid cells as expected (negative control).

Applications for TYRP1 Antibody (CL4906)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. For ICC/IF, PFA/Triton X-100 is recommended for fixation/permeabilization.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TYRP1

TYRP1 encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. [provided by RefSeq]

Alternate Names

b-PROTEIN, CAS25,6-dihydroxyindole-2-carboxylic acid oxidase, Catalase B, CATB, EC 1.14.18, EC 1.14.18.-, EC 1.14.18.1, Glycoprotein 75, GP75DHICA oxidase, Melanoma antigen gp75, TRP-1, TRPTYRP, tyrosinase-related protein 1TRP1, TYRRP

Gene Symbol

TYRP1

Additional TYRP1 Products

Product Documents for TYRP1 Antibody (CL4906)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TYRP1 Antibody (CL4906)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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