U11/U12-35K Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-39082

Novus Biologicals, part of Bio-Techne
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NBP2-39082
NBP2-39082-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all U11/U12-35K Antibodies »

Product Summary for U11/U12-35K Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LGGGLGGKKESGQLRFGGRDRPFRKPINLPVVKNDLYREGKRERRERS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for U11/U12-35K Antibody

Immunohistochemistry: U11/U12-35K Antibody [NBP2-39082]

Immunohistochemistry: U11/U12-35K Antibody [NBP2-39082]

Immunohistochemistry: U11/U12-35K Antibody [NBP2-39082] - Staining of human liver shows moderate nuclear and cytoplasmic positivity in hepatocytes and moderate nuclear positivity in bile duct cells.

Applications for U11/U12-35K Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: U11/U12-35K

The protein encoded by the U1SNRNPBP gene is a homolog of U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal is rich in Arg/Asp and Arg/Glu dipeptides; a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. This gene is differentially expressed in a variety of human tissues. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Alternate Names

HM1, HM-1, MGC138160, Protein HM-1, small nuclear ribonucleoprotein 35kDa (U11/U12), U1 snRNP-binding protein homolog, U11/U12 small nuclear ribonucleoprotein 35 kDa protein, U11/U12 snRNP 35 kDa protein, U11/U12 snRNP 35K, U11/U12-35K, U1-snRNP binding protein homolog, U1SNRNPBPU1 snRNP binding protein homolog

Gene Symbol

SNRNP35

UniProt

Q16560 (Human)

Additional U11/U12-35K Products

Product Documents for U11/U12-35K Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for U11/U12-35K Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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