U2AF1L4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-06996

Novus Biologicals, part of Bio-Techne
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NBP1-06996
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all U2AF1L4 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-EDGERAVAELSNR corresponding to internal region according to NP_659424.2.

Epitope

internal region

Specificity

This antibody is expected to recognise both reported isoforms (NP_001035515.1 and NP_659424.2). No cross-reactivity with U2AF1 expected.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for U2AF1L4 Antibody

Western Blot: U2AF1L4 Antibody [NBP1-06996]

Western Blot: U2AF1L4 Antibody [NBP1-06996]

Western Blot: U2AF1L4 Antibody [NBP1-06996] - Analysis of U2AF1L4 in Human Cerebellum lysate (35ug protein in RIPA buffer) using NBP1-06996 at 0.1ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for U2AF1L4 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 20 kDa band observed in human brain (cerebellum) and lung lysates (calculated MW of 21.3 kDa band according to NP_001035515.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: U2AF1L4

RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutiveand enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required foraccurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participatesin the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T cell activation; anevent reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site

Alternate Names

FLJ35525, MGC33901, splicing factor U2AF 26 kDa subunit, U2 auxiliary factor 26, U2 small nuclear RNA auxiliary factor 1-like 3, U2 small nuclear RNA auxiliary factor 1-like 4, U2 small nuclear RNA auxiliary factor 1-like protein 3, U2 small nuclear RNA auxiliary factor 1-like protein 4, U2(RNU2) small nuclear RNA auxiliary factor 1-like 3, U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3, U2AF1L3, U2AF1L3V1, U2AF1-like protein 3, U2AF1RS3, U2AF1-RS3, U2af26

Entrez Gene IDs

199746 (Human); 233073 (Mouse); 361542 (Rat)

Gene Symbol

U2AF1L4

UniProt

NP_001035515.1 (Human)

Additional U2AF1L4 Products

Product Documents for U2AF1L4 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for U2AF1L4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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