Ubiquilin 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58403

Novus Biologicals, part of Bio-Techne
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NBP2-58403
NBP2-58403-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Ubiquilin 1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: STASGTSGQSTTAPNLVPGVGASMFNTPG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Ubiquilin 1 Antibody

Western Blot: Ubiquilin 1 Antibody [NBP2-58403]

Western Blot: Ubiquilin 1 Antibody [NBP2-58403]

Western Blot: Ubiquilin 1 Antibody [NBP2-58403] - Western blot analysis in human cell line RT-4 and human cell line U-251 MG.
Immunocytochemistry/ Immunofluorescence: Ubiquilin 1 Antibody [NBP2-58403]

Immunocytochemistry/ Immunofluorescence: Ubiquilin 1 Antibody [NBP2-58403]

Immunocytochemistry/Immunofluorescence: Ubiquilin 1 Antibody [NBP2-58403] - Staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.

Applications for Ubiquilin 1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Ubiquilin 1

Ubiquilin 1 encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.

Alternate Names

DA41, PLIC-1, UBQLN1, UBQN, XDRP1

Gene Symbol

UBQLN1

Additional Ubiquilin 1 Products

Product Documents for Ubiquilin 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Ubiquilin 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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