UCH-L1/PGP9.5 Antibody (UCHL1/8107R) [Janelia Fluor® 585]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21061JF585
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Rat
Applications
Immunohistochemistry-Paraffin
Label
Janelia Fluor 585
Antibody Source
Recombinant Monoclonal Rabbit IgG Kappa Clone # UCHL1/8107R
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for UCH-L1/PGP9.5 Antibody (UCHL1/8107R) [Janelia Fluor® 585]
Immunogen
Recombinant full-length human UCH-L1/PGP9.5 protein
Reactivity Notes
Shows a broad species reactivity
Localization
Cytoplasm. Endoplasmic Reticulum membrane
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG Kappa
Applications for UCH-L1/PGP9.5 Antibody (UCHL1/8107R) [Janelia Fluor® 585]
Application
Recommended Usage
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: UCH-L1/PGP9.5
UCH L1 is down-regulated in brains from Parkinson disease and Alzheimer disease patients, and certian site specific mutations in the UCHL1 gene can either increase or decrese the risk of Parkinson's and/or Alzheimer's neurodegenerative diseases.
Human UCHL 1 and the closely related UCHL3 protein have one of the most complicated knot structures ever discovered, with five knot crossings. This knot structure is expected to help the protein resist degradation in the proteasome.
Long Name
Ubiquitin C-terminal Hydrolase L1
Alternate Names
PARK5, PGP9.5, UCHL1
Gene Symbol
UCHL1
Additional UCH-L1/PGP9.5 Products
Product Documents for UCH-L1/PGP9.5 Antibody (UCHL1/8107R) [Janelia Fluor® 585]
Product Specific Notices for UCH-L1/PGP9.5 Antibody (UCHL1/8107R) [Janelia Fluor® 585]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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