UGT8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-62245

Novus Biologicals, part of Bio-Techne
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NBP1-62245
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all UGT8 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to UGT8(UDP glycosyltransferase 8) The peptide sequence was selected from the middle region of UGT8. Peptide sequence GILLEWKTVTEKELYEALVKVINNPSYRQRAQKLSEIHKDQPGHPVNRTI. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for UGT8 Antibody

Western Blot: UGT8 Antibody [NBP1-62245]

Western Blot: UGT8 Antibody [NBP1-62245]

Western Blot: UGT8 Antibody [NBP1-62245] - Human Heart lysate, concentration 0.2-1 ug/ml.

Applications for UGT8 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: UGT8

Galactocerebrosides are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system and are also present in small amounts in kidney. The key enzymatic step in the biosynthesis of galactocerebrosides consists of the transfer of galactose to ceramide catalyzed by UDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45). The enzyme UGT8 is the first involved in complex lipid biosynthesis in the myelinating oligodendrocyte.Galactocerebrosides are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system and are also present in small amounts in kidney. The key enzymatic step in the biosynthesis of galactocerebrosides consists of the transfer of galactose to ceramide catalyzed by UDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45). The enzyme encoded by the CGT gene is the first involved in complex lipid biosynthesis in the myelinating oligodendrocyte.[supplied by OMIM].

Alternate Names

Ceramide UDP-galactosyltransferase, Cerebroside synthase, CGT2-hydroxyacylsphingosine 1-beta-galactosyltransferase, EC 2.4.1, EC 2.4.1.45, UDP glycosyltransferase 8, UDP-galactose ceramide galactosyltransferase, UDP-galactose-ceramide galactosyltransferase, UGT4, uridine diphosphate glycosyltransferase 8

Gene Symbol

UGT8

UniProt

Q16880 (Human)

Additional UGT8 Products

Product Documents for UGT8 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for UGT8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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