ULBP-1 Antibody (MM0592-10K10) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-11986

Novus Biologicals, part of Bio-Techne
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NBP2-11986
NBP2-11986-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Block/Neutralize, CyTOF-ready, Flow Cytometry

Cited:

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2 Clone # MM0592-10K10

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all ULBP-1 Antibodies »

Product Specifications

Immunogen

Human recombinant ULBP-1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2

Applications for ULBP-1 Antibody (MM0592-10K10) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:50-1:100
Application Notes
This antibody has been used to neutralize ligand/receptor interaction. This antibody is CyTOF ready.

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ULBP-1

Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signalingpathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands toNKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked theinteraction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system.UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface

Long Name

UL16 Binding Protein-1

Alternate Names

ALCAN-beta, MULT-1, NKG2DL, NKG2DL1, RAET1I, ULBP1

Gene Symbol

ULBP1

UniProt

Q9BZM6 (Human)

Additional ULBP-1 Products

Product Documents for ULBP-1 Antibody (MM0592-10K10) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ULBP-1 Antibody (MM0592-10K10) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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