ULBP-2 Antibody (022)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90060

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-90060-100ul
NBP2-90060-50ul
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 022

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ULBP-2 Antibodies »

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human ULBP-2 (Uniprot#: Q9BZM5; Met1-Ser217).

Specificity

No cross-reactivity in ELISA with: Human ULBP1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for ULBP-2 Antibody (022)

Immunohistochemistry-Paraffin: ULBP-2 Antibody (022) [NBP2-90060]

Immunohistochemistry-Paraffin: ULBP-2 Antibody (022) [NBP2-90060]

Immunohistochemistry-Paraffin: ULBP-2 Antibody (022) [NBP2-90060] - Staining of human ULBP2 in human renal carcinoma with rabbit monoclonal antibody (1:200).
Immunohistochemistry-Paraffin: ULBP-2 Antibody (022) [NBP2-90060]

Immunohistochemistry-Paraffin: ULBP-2 Antibody (022) [NBP2-90060]

Immunohistochemistry-Paraffin: ULBP-2 Antibody (022) [NBP2-90060] - Staining of human ULBP2 in human gastric cancer with rabbit monoclonal antibody (1:200).
Immunohistochemistry-Paraffin: ULBP-2 Antibody (022) [NBP2-90060]

Immunohistochemistry-Paraffin: ULBP-2 Antibody (022) [NBP2-90060]

Immunohistochemistry-Paraffin: ULBP-2 Antibody (022) [NBP2-90060] - Staining of human ULBP2 in human hepatoma with rabbit monoclonal antibody (1:200).

Applications for ULBP-2 Antibody (022)

Application
Recommended Usage

Immunohistochemistry

1:100-1:500

Immunohistochemistry-Paraffin

1:100-1:500

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ULBP-2

Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signalingpathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands toNKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked theinteraction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system.UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface

Long Name

UL16 Binding Protein-2

Alternate Names

ALCAN-alpha, N2DL2, NKG2DL2, RAET1H, ULBP2

Gene Symbol

ULBP2

Additional ULBP-2 Products

Product Documents for ULBP-2 Antibody (022)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ULBP-2 Antibody (022)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.