uPAR Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14711

Novus Biologicals, part of Bio-Techne
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NBP2-14711
NBP2-14711-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all uPAR Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: VRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for uPAR Antibody

Immunohistochemistry-Paraffin: uPAR Antibody [NBP2-14711]

Immunohistochemistry-Paraffin: uPAR Antibody [NBP2-14711]

Immunohistochemistry-Paraffin: uPAR Antibody [NBP2-14711] - Staining of human small intestine shows moderate cytoplasmic positivity in lymphoid cells.
Immunohistochemistry-Paraffin: uPAR Antibody [NBP2-14711]

Immunohistochemistry-Paraffin: uPAR Antibody [NBP2-14711]

Immunohistochemistry-Paraffin: uPAR Antibody [NBP2-14711] - Staining of human bone marrow shows moderate cytoplasmic positivity in hematopoietic cells.
Immunohistochemistry-Paraffin: uPAR Antibody [NBP2-14711]

Immunohistochemistry-Paraffin: uPAR Antibody [NBP2-14711]

Immunohistochemistry-Paraffin: uPAR Antibody [NBP2-14711] - Staining of human lung shows moderate cytoplasmic positivity in macrophages.
View 1 more images

Applications for uPAR Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: uPAR

uPAR (Urokinase plasminogen activator receptor) is a glycoprotein I anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum beta globulin plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.

Long Name

Urokinase-type Plasminogen Activator Receptor

Alternate Names

PLAUR

Gene Symbol

PLAUR

Additional uPAR Products

Product Documents for uPAR Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for uPAR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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