USP11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80639

Novus Biologicals, part of Bio-Techne
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NBP1-80639
NBP1-80639-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all USP11 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VEPQEDTRLWAKNSEGSLDRLYDTHITVLDAALETGQLIIMETRKKDGTWPSAQLHVMNNNMSEEDEDFKGQPGICGLTNLGNT

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (83%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for USP11 Antibody

Immunohistochemistry-Paraffin: USP11 Antibody [NBP1-80639]

Immunohistochemistry-Paraffin: USP11 Antibody [NBP1-80639]

Immunohistochemistry-Paraffin: USP11 Antibody [NBP1-80639] - Staining of human testis shows strong nuclear positivity in a subset of cells in seminiferous ducts.
Immunohistochemistry-Paraffin: USP11 Antibody [NBP1-80639]

Immunohistochemistry-Paraffin: USP11 Antibody [NBP1-80639]

Immunohistochemistry-Paraffin: USP11 Antibody [NBP1-80639] - Staining of human cerebellum, cerebral cortex, skeletal muscle and testis using Anti-USP11 antibody NBP1-80639 (A) shows similar protein distribution across tissues to independent antibody NBP1-80640 (B).
Immunohistochemistry-Paraffin: USP11 Antibody [NBP1-80639]

Immunohistochemistry-Paraffin: USP11 Antibody [NBP1-80639]

Immunohistochemistry-Paraffin: USP11 Antibody [NBP1-80639] - Analysis in human cerebral cortex and skeletal muscle tissues. Corresponding USP11 RNA-seq data are presented for the same tissues.
View 5 more images

Applications for USP11 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: USP11

Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23

Long Name

Ubiquitin Specific Protease 11

Alternate Names

Ubiquitin Thioesterase 11, UHX1

Entrez Gene IDs

8237 (Human)

Gene Symbol

USP11

UniProt

P51784

Additional USP11 Products

Product Documents for USP11 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for USP11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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