V2 Vasopressin R/AVPR2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89072

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse

Applications

Validated:

ELISA, Immunohistochemistry, Western Blot

Cited:

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all V2 Vasopressin R/AVPR2 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to the sequence near the N-terminus of rat V2 Vasopressin R/AVPR2.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for V2 Vasopressin R/AVPR2 Antibody

Western Blot: V2 Vasopressin R/AVPR2 Antibody [NBP2-89072]

Western Blot: V2 Vasopressin R/AVPR2 Antibody [NBP2-89072]

Western Blot: V2 Vasopressin R/AVPR2 Antibody [NBP2-89072] - Western blot analysis: MW Marker (1) and 20ug of rat kidney extract (2), probed with Vasopressin Receptor (V2) pAb at 2ug/ml.

Applications for V2 Vasopressin R/AVPR2 Antibody

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS containing 50% glycerol

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: V2 Vasopressin R/AVPR2

The human AVPR2 locus encodes vasopressin receptor type 2, a member of the vasopressin/oxytocin family subfamily. V2 receptor has been shown to concentrate the urine and maintain water homeostasis by responding to the pituitary hormone arginine vasopressin (AVP). Loss of gene function results in the disease Nephrogenic Diabetes Insipidus (NDI). When extrarenal V2 receptors are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known; its absence does not appear to be detrimental in NDI patients. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts. The V2 Receptor is also expressed outside the kidney although its tissue localization is uncertain. AVPR2 expression has also been described in brain, breast, fetal lung tissue and lung cancer associated with alternative splicing. ESTs have been isolated from normal lung and pancreatic cancer libraries.

Long Name

Arginine Vasopressin Receptor 2

Alternate Names

ADHR, AVPR2, DI1, DIR3, NDI, V2 VasopressinR, V2R

Gene Symbol

AVPR2

Additional V2 Vasopressin R/AVPR2 Products

Product Documents for V2 Vasopressin R/AVPR2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for V2 Vasopressin R/AVPR2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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