Vang-like Protein 2/VANGL2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81428

Novus Biologicals, part of Bio-Techne
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NBP1-81428
NBP1-81428-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Vang-like Protein 2/VANGL2 Antibodies »

Product Summary for Vang-like Protein 2/VANGL2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QLQPQFTLKVVRSTDGASRFYNVGHLSIQRVAVWILEKYYHDFPVYNPALLNLPKSVLAKKVSGFKVYSLGEENSTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Vang-like Protein 2/VANGL2 Antibody

Immunohistochemistry-Paraffin: Vang-like Protein 2/VANGL2 Antibody [NBP1-81428]

Immunohistochemistry-Paraffin: Vang-like Protein 2/VANGL2 Antibody [NBP1-81428]

Immunohistochemistry-Paraffin: Vang-like Protein 2/VANGL2 Antibody [NBP1-81428] - Staining of human tonsil shows strong cytoplasmic positivity in reaction center cells.

Applications for Vang-like Protein 2/VANGL2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Vang-like Protein 2/VANGL2

VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. The VANGL2 gene encodes a homolog of Drosophila 'strabismus/Van Gogh' (Stbm/Vang), a component of the frizzled-dishevelled tissue polarity pathway.[supplied by OMIM]

Alternate Names

LPP1, LTAP, STB1, STBM, Strabismus, Vang like Protein 2, VANGL2

Gene Symbol

VANGL2

Additional Vang-like Protein 2/VANGL2 Products

Product Documents for Vang-like Protein 2/VANGL2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Vang-like Protein 2/VANGL2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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