Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Vasohibin Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human VASH1. The immunogen is located within amino acids 290 - 340 of VASH1. Amino Acid Squence: KIGKGTGPPSPTKDRKKDV

Specificity

VASH1 antibody is predicted to not cross-react with other vasohibin protein family members. At least two isoforms are known to exist; this antibody will recognize only the long isoform.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Vasohibin Antibody - BSA Free

Western Blot: Vasohibin AntibodyBSA Free [NBP1-76579]

Western Blot: Vasohibin AntibodyBSA Free [NBP1-76579]

Western Blot: Vasohibin Antibody [NBP1-76579] - Western blot analysis of VASH1 in human brain tissue lysate with VASH1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Vasohibin Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Vasohibin Antibody - BSA Free [NBP1-76579] -

Immunocytochemistry/ Immunofluorescence: Vasohibin Antibody - BSA Free [NBP1-76579] - Immunofluorescence of Vasohibin in mouse brain tissue with Vasohibin antibody at 20 ug/mL.
Vasohibin Antibody - BSA Free

Immunohistochemistry: Vasohibin Antibody - BSA Free [NBP1-76579] -

Immunohistochemistry: Vasohibin Antibody - BSA Free [NBP1-76579] - Immunohistochemistry of Vasohibin in mouse brain tissue with Vasohibin antibody at 5 ug/mL.

Applications for Vasohibin Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Vasohibin

VASH1 was originally identified as an endothelium-derived vascular endothelial growth factor (VEGF)-inducible angiogenesis inhibitor that acts in a negative feedback manner. VASH1 mRNA is expressed brain, heart, kidney and placenta in the adult, with robust expression in various organs during embryonic development. VASH1 expression in tumor cells and tumor vasculature is silenced by methylation by increased expression of Zeste homolog 2 (EZH2). The increase of EZH2 expression is induced by VEGF stimulation, leading to poor clinical prognosis. Recombinant adenovirus expressing VASH prevented tumor angiogenesis and inhibited tumor growth, suggesting that it may be a potentially valuable antitumor therapy in the clinic.

Alternate Names

KIAA1036, VASH1

Gene Symbol

VASH1

UniProt

NP_055724

Additional Vasohibin Products

Product Documents for Vasohibin Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Vasohibin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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