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VDAC1 Antibody (S05-7F2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14982

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-14982-100ul
NBP3-14982-25ul

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S05-7F2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthetic peptide of human VDAC1 (Uniprot#: P21796)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for VDAC1 Antibody (S05-7F2)

Western Blot: VDAC1 Antibody (S05-7F2) [NBP3-14982]

Western Blot: VDAC1 Antibody (S05-7F2) [NBP3-14982]

Western Blot: VDAC1 Antibody (S05-7F2) [NBP3-14982] - Western blot detection of VDAC1 in Jurkat, Rat Brain, C6 cell lysates using VDAC1 Rabbit mAb (1:1000 diluted). Predicted band size: 31kDa. Observed band size: 31kDa.
Immunohistochemistry-Paraffin: VDAC1 Antibody (S05-7F2) [NBP3-14982]

Immunohistochemistry-Paraffin: VDAC1 Antibody (S05-7F2) [NBP3-14982]

Immunohistochemistry-Paraffin: VDAC1 Antibody (S05-7F2) [NBP3-14982] - Immunohistochemistry of VDAC1 in paraffin-embedded Human colon cancer tissue using VDAC1 Rabbit mAb at dilution 1/5
Western Blot: VDAC1 Antibody (S05-7F2) [NBP3-14982]

Western Blot: VDAC1 Antibody (S05-7F2) [NBP3-14982]

Western Blot: VDAC1 Antibody (S05-7F2) [NBP3-14982] - Western blot detection of VDAC1 in 293 cell lysates using VDAC1 Rabbit mAb (1:1000 diluted). Predicted band size: 31KDa. Observed band size: 31KDa.

Applications for VDAC1 Antibody (S05-7F2)

Application
Recommended Usage

Immunohistochemistry

1/20-1/500

Western Blot

1/2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VDAC1

VDAC1 is an outer membrane mitochondrial protein. The VDAC proteins are thought to form aqueous channels, or pores, through which adenine nucleotides cross the outer mitochondrial membrane. VDACs have been implicated in the formation of the mitochondrial permeability transition pore complex in apoptotic cells. This complex, formed by VDAC, adenine nucleotide translocator (ANT), and cyclophilin D (CypD), is thought to allow the mitochondria to undergo metabolic uncoupling and irreversible morphologic changes that ultimately destroy the mitochondria during apoptosis. VDACs are highly expressed in heart, liver and skeletal muscle, where concentrations of mitochondria are at their highest.

Long Name

Voltage-dependent anion-selective channel protein 1

Alternate Names

hVDAC1, Plasmalemmal porin, Porin 31HL, Porin 31HM, VDAC, VDAC-1

Gene Symbol

VDAC1

Additional VDAC1 Products

Product Documents for VDAC1 Antibody (S05-7F2)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for VDAC1 Antibody (S05-7F2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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