VDAC1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-45921

Novus Biologicals, part of Bio-Techne
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NBP1-45921-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Bovine, Rabbit

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all VDAC1 Antibodies »

Product Summary for VDAC1 Antibody

Immunogen

Synthetic peptide surrounding amino acid 189 of human VDAC.

Marker

Mitochondria Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for VDAC1 Antibody

Western Blot: VDAC1 Antibody [NBP1-45921]

Western Blot: VDAC1 Antibody [NBP1-45921]

Western Blot: VDAC1 Antibody [NBP1-45921] - Analysis of VDAC/Porin with 3T3 cell lysate.

Applications for VDAC1 Antibody

Application
Recommended Usage

Immunohistochemistry

2.5 ug/mL

Western Blot

0.5 - 4 ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2), 0.5% BSA, 30% Glycerol

Preservative

0.01% Thimerosal

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: VDAC1

Voltage dependent anion selective channel protein 1 (VDAC/Porin) belongs to the eukaryotic mitochondrial porin family and forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel allows diffusion of small hydrophilic molecules; it adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation selective. VDAC/Porin expression is observed in the heart,liver and skeletal muscle.

Long Name

Voltage-dependent anion-selective channel protein 1

Alternate Names

hVDAC1, Plasmalemmal porin, Porin 31HL, Porin 31HM, VDAC, VDAC-1

Entrez Gene IDs

7416 (Human); 22333 (Mouse); 83529 (Rat); 282119 (Bovine); 100008751 (Rabbit)

Gene Symbol

VDAC1

UniProt

P21796 (Human)

Additional VDAC1 Products

Product Documents for VDAC1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for VDAC1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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