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VDAC2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12109

Novus Biologicals, part of Bio-Techne
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NBP3-12109

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic peptide from the C-terminal domain of human VDAC3 (P45880)

Epitope

C-terminal domain of human protein

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for VDAC2 Antibody

Immunohistochemistry-Paraffin: VDAC2 Antibody [NBP3-12109]

Immunohistochemistry-Paraffin: VDAC2 Antibody [NBP3-12109]

Immunohistochemistry-Paraffin: VDAC2 Antibody [NBP3-12109] - Formalin-Fixed, Paraffin-Embedded HIER human heartusing 10 mM sodium citrate buffer pH 6.0

Applications for VDAC2 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

10 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: VDAC2

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. Interacts with hexokinases. It is present in the outer mitochondrial membrane. There are 4 isoforms as result of alternative splicing. Expressed in all tissues examined. Consists mainly of membrane spanning sided beta sheets. Belongs to the eukaryotic mitochondrial porin family.

Alternate Names

FLJ23841, hVDAC2, Outer mitochondrial membrane protein porin 2, POR, VDAC-2, voltage-dependent anion channel 2, voltage-dependent anion-selective channel protein 2

Gene Symbol

VDAC2

Additional VDAC2 Products

Product Documents for VDAC2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for VDAC2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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