VEGF-D Antibody (MM0007-7E79) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB110-60973

Novus Biologicals, part of Bio-Techne
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NB110-60973
NB110-60973-0.025mg
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2 Clone # MM0007-7E79

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all VEGF-D Antibodies »

Product Specifications

Immunogen

Human recombinant VEGF-D

Specificity

VEGFD (MM0007-7E79). No cross-reactivity is shown with VEGF and VEGF-B.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2

Scientific Data Images for VEGF-D Antibody (MM0007-7E79) - Azide and BSA Free

Immunohistochemistry-Paraffin: VEGF-D Antibody (MM0007-7E79) - Azide and BSA Free [NB110-60973]

Immunohistochemistry-Paraffin: VEGF-D Antibody (MM0007-7E79) - Azide and BSA Free [NB110-60973]

Immunohistochemistry-Paraffin: VEGFD Antibody (MM0007-7E79) [NB110-60973] - Formalin fixed and Paraffin embedded human placenta tissue section was subjected to IHC staining (Proteinase K pretreatment is required).
Immunohistochemistry-Paraffin: VEGF-D Antibody (MM0007-7E79) - Azide and BSA Free [NB110-60973]

Immunohistochemistry-Paraffin: VEGF-D Antibody (MM0007-7E79) - Azide and BSA Free [NB110-60973]

Immunohistochemistry-Paraffin: VEGFD Antibody (MM0007-7E79) [NB110-60973] - Formalin fixed and Paraffin embedded human placenta tissue section was subjected to IHC staining using NB110-60973 (Proteinase K pretreatment is required).

Applications for VEGF-D Antibody (MM0007-7E79) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200-1:500

Immunohistochemistry-Paraffin

1:200-1:500

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: VEGF-D

Vascular Endothelial Growth Factor D (VEGFD), also known as c-fos-induced growth factor (FIGF), is a member of the VEGF family of growth factors. Vascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. VEGFD is most closely related to VEGFC (23.3% amino acid sequence identity) and has a similar VEGF homology domain that spans the middle third of the precursor protein and the long N-terminal and C-terminal extensions. In adults, VEGFD is highly expressed in lung, heart, muscle, and small intestine. VEGFD expression in fibroblasts is induced by cell interaction mediated by cadherin 11. Recombinant human VEGFD is a ligand for the tyrosine kinases, VEGFR2 (Flk1) and VEGF receptor 3 (Flt4). Since VEGFR3 is strongly expressed in lymphatic endothelial cells, it is postulated that VEGFD is involved in the regulation of the growth and/or differentiation of lymphatic endothelium and thus, a mitogen for endothelial cells.

Long Name

Vascular Endothelial Growth Factor D/cFos-induced Growth Factor

Alternate Names

FIGF, VEGFD

Entrez Gene IDs

2277 (Human)

Gene Symbol

VEGFD

UniProt

O43915

Additional VEGF-D Products

Product Documents for VEGF-D Antibody (MM0007-7E79) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for VEGF-D Antibody (MM0007-7E79) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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