VEGFR1/Flt-1 Antibody (CL0344)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-52919

Novus Biologicals, part of Bio-Techne
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NBP2-52919
NBP2-52919-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL0344

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all VEGFR1/Flt-1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LNLTIMNVSLQDSGTYACRARNVYTGEEILQKKEITIRDQEAPYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFIERVTEEDEGVYHCKATNQKGS

Epitope

EPQITWFKNN

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (82%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for VEGFR1/Flt-1 Antibody (CL0344)

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody (CL0344) [NBP2-52919]

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody (CL0344) [NBP2-52919]

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody (CL0344) [NBP2-52919] - Staining in human placenta and tonsil tissues. Corresponding FLT1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody (CL0344) [NBP2-52919]

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody (CL0344) [NBP2-52919]

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody (CL0344) [NBP2-52919] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody (CL0344) [NBP2-52919]

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody (CL0344) [NBP2-52919]

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody (CL0344) [NBP2-52919] - Staining of human kidney shows strong cytoplasmic positivity in endothelial cells.
View 2 more images

Applications for VEGFR1/Flt-1 Antibody (CL0344)

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VEGFR1/Flt-1

Receptors for VEGF, VEGFB and PGF have tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. VEGF and its high-affinity binding receptors--the tyrosine kinases FLK1 and FLT1--are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis.

Long Name

Vascular Endothelial Growth Factor Receptor 1

Alternate Names

Flt-1, FLT1, FRT, VEGF R1, VEGFR-1

Gene Symbol

FLT1

Additional VEGFR1/Flt-1 Products

Product Documents for VEGFR1/Flt-1 Antibody (CL0344)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for VEGFR1/Flt-1 Antibody (CL0344)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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