Skip to main content

VEGFR1/Flt-1 Antibody - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-18631

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
Loading...
NBP1-18631-0.02mg

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

A peptide of the C-terminal end of native human soluble VEGFR-1/Flt-1 (GEHCNKKAVFSRISKFKSTR NDSTTQSNVKH)

Specificity

soluble VEGFR-1/Flt-1

Marker

Endothelial Cell Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for VEGFR1/Flt-1 Antibody - Azide and BSA Free

Western Blot: VEGFR1/Flt-1 Antibody [NBP1-18631]

Western Blot: VEGFR1/Flt-1 Antibody [NBP1-18631]

Western Blot: VEGFR1/Flt-1 Antibody [NBP1-18631] - The polyclonal antibody was raised against the unique C-terminal end of the native human soluble Flt-1 (amino acids: CNKKAVFSRISKFKSTRNDSTTQSNVKH). The Protein-A purified antibody recognizes the recombinant soluble Flt-1 (native) but not the recombinant soluble Flt-1(D1-5) both produced in insect cells. Because of the different glycosylation of insect cells compared to mammalian cells the MW of sFlt-1 (native) is about 96 kDa instead of about 110 kDa of the naturally occurring sFlt-1. The antibody did not cross react with recombinant human soluble KDR (D1-7). The monoclonal anti-human VEGFR-1/Flt-1 antibody raised against the first 5 Ig-like loops of Flt-1 recognizes both forms.

Applications for VEGFR1/Flt-1 Antibody - Azide and BSA Free

Application
Recommended Usage

Western Blot

1-5 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. Please note the sample size of this product will be provided in reconstituted liquid form.

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VEGFR1/Flt-1

VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes.

Long Name

Vascular Endothelial Growth Factor Receptor 1

Alternate Names

Flt-1, FLT1, FRT, VEGF R1, VEGFR-1

Entrez Gene IDs

2321 (Human)

Gene Symbol

FLT1

Additional VEGFR1/Flt-1 Products

Product Documents for VEGFR1/Flt-1 Antibody - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for VEGFR1/Flt-1 Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Loading...
Loading...
Loading...
Loading...
Loading...