VGLUT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52551

Novus Biologicals, part of Bio-Techne
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NBP1-52551
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (93%), Monkey (100%), Mouse (93%), Porcine (93%), Primate (93%), Rabbit (93%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all VGLUT1/SLC17A7 Antibodies »

Product Specifications

Immunogen

Synthetic peptide C-HDQLAGSDDSEMED from an internal region of human VGLUT1 (NP_064705.1).

Epitope

C-HDQLAGSDDSEMED from an internal region

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (93%), Hamster (86%), Canine (86%), Equine (86%).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for VGLUT1 Antibody

Immunohistochemistry-Paraffin: VGLUT1 Antibody [NBP1-52551]

Immunohistochemistry-Paraffin: VGLUT1 Antibody [NBP1-52551]

Immunohistochemistry-Paraffin: VGLUT1 Antibody [NBP1-52551] - Analysis of anti-SLC17A7 / VGLUT1 antibody with human adrenal cortex at concentration 3.75 ug/ml.

Applications for VGLUT1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

3.75 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS (pH 7.3) and 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VGLUT1/SLC17A7

VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate. Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate.

Long Name

Vesicular Glutamate Transporter 1

Alternate Names

BNPI, SLC17A7

Entrez Gene IDs

57030 (Human)

Gene Symbol

SLC17A7

UniProt

Q9P2U7

Additional VGLUT1/SLC17A7 Products

Product Documents for VGLUT1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for VGLUT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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