VIAAT/SLC32A1/VGAT Antibody (CL2793)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46628

Novus Biologicals, part of Bio-Techne
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NBP2-46628
NBP2-46628-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL2793

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all VIAAT/SLC32A1 Antibodies »

Product Summary for VIAAT/SLC32A1/VGAT Antibody (CL2793)

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence ATSVSNKSQAKMSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQGLQMDILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPLPPSGSKDQVG

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for VIAAT/SLC32A1/VGAT Antibody (CL2793)

Immunohistochemistry: VIAAT/SLC32A1/VGAT Antibody (CL2793) [NBP2-46628]

Immunohistochemistry: VIAAT/SLC32A1/VGAT Antibody (CL2793) [NBP2-46628]

Immunohistochemistry: VIAAT/SLC32A1/VGAT Antibody (2793) [NBP2-46628] - Staining of rat basal forebrain shows strong positivity in GABAergic fibers in the globus pallidus.
Immunohistochemistry-Paraffin: VIAAT/SLC32A1/VGAT Antibody (CL2793) [NBP2-46628]

Immunohistochemistry-Paraffin: VIAAT/SLC32A1/VGAT Antibody (CL2793) [NBP2-46628]

Immunohistochemistry-Paraffin: VIAAT/SLC32A1/VGAT Antibody (2793) [NBP2-46628] - Staining of human midbrain shows positivity in GABAergic fibers in substantia nigra, pars reticulata.
Immunohistochemistry: VIAAT/SLC32A1/VGAT Antibody (CL2793) [NBP2-46628]

Immunohistochemistry: VIAAT/SLC32A1/VGAT Antibody (CL2793) [NBP2-46628]

Immunohistochemistry: VIAAT/SLC32A1/VGAT Antibody (2793) [NBP2-46628] - Staining of mouse brain shows moderate positivity in GABAergic processes in the cerebellum.
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Applications for VIAAT/SLC32A1/VGAT Antibody (CL2793)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VIAAT/SLC32A1

The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles(McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Acid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).

Long Name

Vesicular Inhibitory Amino Acid Transporter

Alternate Names

SLC32A1, VGAT

Entrez Gene IDs

140679 (Human)

Gene Symbol

SLC32A1

UniProt

Q9H598 (Human)

Additional VIAAT/SLC32A1 Products

Product Documents for VIAAT/SLC32A1/VGAT Antibody (CL2793)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for VIAAT/SLC32A1/VGAT Antibody (CL2793)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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