Vitronectin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38901

Novus Biologicals, part of Bio-Techne
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NBP2-38901
NBP2-38901-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Vitronectin Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: KCQCDELCSYYQSCCTDYTAECKPQVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Vitronectin Antibody

Immunocytochemistry/ Immunofluorescence: Vitronectin Antibody [NBP2-38901]

Immunocytochemistry/ Immunofluorescence: Vitronectin Antibody [NBP2-38901]

Immunocytochemistry/Immunofluorescence: Vitronectin Antibody [NBP2-38901] - Staining of human cell line CACO-2 shows localization to endoplasmic reticulum & vesicles.
Immunohistochemistry-Paraffin: Vitronectin Antibody [NBP2-38901]

Immunohistochemistry-Paraffin: Vitronectin Antibody [NBP2-38901]

Immunohistochemistry-Paraffin: Vitronectin Antibody [NBP2-38901] - Staining of human kidney shows distinct positivity in plasma.

Applications for Vitronectin Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Vitronectin

Vitronectin also called serum spreading factor or complement S-protein, is a member of the pexin family (1). Found in serum and in tissues, Vitronectin exist in two forms; as a single chain (75kDa) and as a clipped form composed of two chains (65kDa and 10kDa). Vitronectin promotes cell adhesion, spreading and migration through specific interactions with cellular integrins, and inhibits cytolysis by the complement C5b-9 complex (2-4). Vitronectin also interacts with several critical proteins that regulate thrombosis and fibrinolysis. Vitronectin is phosphorylated by PKA and CKII (5).

Alternate Names

Complement S-protein, Serum Spreading Factor, Somatomedin B, VTN

Entrez Gene IDs

7448 (Human)

Gene Symbol

VTN

UniProt

P04004 (Human)

Additional Vitronectin Products

Product Documents for Vitronectin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Vitronectin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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