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Key Product Details

Species Reactivity

Validated:

Human, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Lambda Clone # VLDLR/1337

Concentration

0.2 mg/ml

Product Summary for VLDLR Antibody (VLDLR/1337)

Immunogen

Recombinant human VLDLR fragment from c-terminal (Uniprot: P98155)

Localization

Cytoplasmic

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 Lambda

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-54553)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for VLDLR Antibody (VLDLR/1337)

Immunohistochemistry-Paraffin: VLDLR Antibody (VLDLR/1337) [NBP2-53351]

Immunohistochemistry-Paraffin: VLDLR Antibody (VLDLR/1337) [NBP2-53351]

Immunohistochemistry-Paraffin: VLDLR Antibody (VLDLR/1337) [NBP2-53351] - Formalin-fixed, paraffin-embedded human Pancreas stained with VLDL-Receptor Monoclonal Antibody (VLDLR/1337).

Applications for VLDLR Antibody (VLDLR/1337)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: VLDLR

VLDL (very low density lipoprotein) cholesterol is one of the three major types of cholesterol found in blood. VLDL receptor plays an essential role in triglyceride metabolism. It binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.

Long Name

Very Low Density Lipoprotein Receptor

Alternate Names

CHRMQ1, VLDL R, VLDLRCH

Gene Symbol

VLDLR

UniProt

Additional VLDLR Products

Product Documents for VLDLR Antibody (VLDLR/1337)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for VLDLR Antibody (VLDLR/1337)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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