VMAT2 Antibody (CL13157)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18556

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # CL13157

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all VMAT2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a sythetic peptide for Q05940. Actual immunogen sequence is proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for VMAT2 Antibody (CL13157)

Western Blot: VMAT2 Antibody (CL13157) [NBP3-18556]

Western Blot: VMAT2 Antibody (CL13157) [NBP3-18556]

Western Blot: VMAT2 Antibody (CL13157) [NBP3-18556] - Analysis in human cell line HEL.
Immunohistochemistry-Paraffin: VMAT2 Antibody (CL13157) [NBP3-18556]

Immunohistochemistry-Paraffin: VMAT2 Antibody (CL13157) [NBP3-18556]

Immunohistochemistry-Paraffin: VMAT2 Antibody (CL13157) [NBP3-18556] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: VMAT2 Antibody (CL13157) [NBP3-18556]

Immunohistochemistry-Paraffin: VMAT2 Antibody (CL13157) [NBP3-18556]

Immunohistochemistry-Paraffin: VMAT2 Antibody (CL13157) [NBP3-18556] - Staining of human dorsal raphe nucleus shows strong cytoplasmic positivity in neurons.
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Applications for VMAT2 Antibody (CL13157)

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

1 ug/ml
Application Notes
For use with IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VMAT2

VMAT2 (Vesicular amine transporter 2) acts to accumulate cytosolic monoamines into synaptic vesicles. Its function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders such as dementia with Lewy bodies. The transporter is a site of action of important drugs, including reserpine and tetrabenazine.

Long Name

Vesicular Monoamine Transporter 2/Solute Carrier Family 18, Member 2

Alternate Names

MNAT, SLC18A2, SVAT, SVMT, VAT2

Gene Symbol

SLC18A2

Additional VMAT2 Products

Product Documents for VMAT2 Antibody (CL13157)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for VMAT2 Antibody (CL13157)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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