VPS4B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49263

Novus Biologicals, part of Bio-Techne
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NBP2-49263
NBP2-49263-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all VPS4B Antibodies »

Product Summary for VPS4B Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: AQKPVKEGQPSPADEKGNDSDGEGESDDPE

Reactivity Notes

Mouse (80%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for VPS4B Antibody

Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263]

Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263]

Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263] - Staining of human endometrium shows moderate granular cytoplasmic positivity in in glandular cells.
Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263]

Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263]

Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263] - Staining of human duodenum shows strong granular cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263]

Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263]

Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263] - Staining of human urinary bladder shows moderate granular cytoplasmic positivity in in urothelial cells.
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Applications for VPS4B Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VPS4B

VPS4B is encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq]

Alternate Names

Cell migration-inducing gene 1 protein, Protein SKD1, SKD1B, SKD1cell migration-inducing 1, Suppressor of K(+) transport growth defect 1, suppressor of K+ transport defect 1, vacuolar protein sorting 4 homolog B (S. cerevisiae), vacuolar protein sorting 4B, vacuolar protein sorting 4B (yeast), vacuolar protein sorting-associated protein 4B, VPS42, VPS4-2

Gene Symbol

VPS4B

Additional VPS4B Products

Product Documents for VPS4B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for VPS4B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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