WASF1/WAVE1 Antibody (S03-5K1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15110

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15110-100ul
NBP3-15110-25ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S03-5K1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all WASF1/WAVE1 Antibodies »

Product Specifications

Immunogen

Recombinant protein of human WASF1/WAVE1 (Uniprot#: Q92558)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

90 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for WASF1/WAVE1 Antibody (S03-5K1)

Western Blot: WASF1/WAVE1 Antibody (S03-5K1) [NBP3-15110]

Western Blot: WASF1/WAVE1 Antibody (S03-5K1) [NBP3-15110]

Western Blot: WASF1/WAVE1 Antibody (S03-5K1) [NBP3-15110] - Western blot detection of WASF1/WAVE1 in Rat Brain, C6, 3T3, Hela cell lysates using WASF1/WAVE1 Rabbit mAb (1:1000 diluted). Predicted band size: 62kDa. Observed band size: 90kDa.

Applications for WASF1/WAVE1 Antibody (S03-5K1)

Application
Recommended Usage

Western Blot

1/1000-1/5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: WASF1/WAVE1

WASP (for Wiskott-Aldrich syndrome protein), N-WASP are downstream effectors of Cdc42 that are implicated in actin polymerization and cytoskeletal organization. The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the actin cytoskeleton. The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating actin reorganization downstream of the Rho family of small GTPases. The two protein homologs WAVE1 and WAVE2 specifically regulate membrane ruffling by inducing the formation of actin filament clusters in response to GTP binding and activating Rac. The WAVE proteins mediate this actin polymerization by cooperating with the Arp2/3 complex, a nucleation core, and thereby promoting the formation of actin filaments. WAVE1, which is also designated SCAR (for suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed with the expression highest in peripheral blood leukocytes.

Long Name

Wiskott-Aldrich Syndrome Protein Family Member 1

Alternate Names

SCAR1, WASP1, WAVE1

Gene Symbol

WASF1

Additional WASF1/WAVE1 Products

Product Documents for WASF1/WAVE1 Antibody (S03-5K1)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for WASF1/WAVE1 Antibody (S03-5K1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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