WDR73 Antibody

Western Blot: WDR73 Antibody [NBP1-82219]

Western Blot: WDR73 Antibody [NBP1-82219] - WDR73 expression in human brain and NCS cells. Immunoblot of WDR73 from NHDFs and dermal fibroblasts from a heterozygous (WDR73 +/p.Phe296Leufs*26) parent of a child with NCS. Note the additional lower molecular mass band for the truncated WDR73 in the heterozygous parent's cell lysate. Image collected and cropped by CiteAb from the following publication (https://academic.oup.com/brain/article-lookup/doi/10.1093/brain/awv153), licensed under a CC-BY license.

Immunocytochemistry/ Immunofluorescence: WDR73 Antibody [NBP1-82219]

Immunocytochemistry/Immunofluorescence: WDR73 Antibody [NBP1-82219] - WDR73 immunoreactivity in fibroblasts from a child with NCS & a heterozygous parent. (A) Anti-WDR73 (green) immunoreactivity is diffuse & cytosolic during interphase (anti-alpha-tubulin, red). (B) WDR73 immunoreactivity localizes to spindle poles & spindle microtubules during metaphase. (C) WDR73 immunoreactivity at mitotic spindle poles, kinetochore microtubules & central spindle microtubules during anaphase. (D) WDR73 immunoreactivity localizes to midbody microtubules apposing the Flemming body. (E-H) WDR73 immunoreactivity is weak and cytosolic in NCS fibroblasts homozygous for WDR73. (E and F) 22% of NCS fibroblasts were binucleate & an additional 20% displayed abnormal nuclear morphology. Scale bars: 10 um (A-D); 50 um (E-F). Image collected and cropped by CiteAb from the following publication (https://academic.oup.com/brain/article-lookup/doi/10.1093/brain/awv153), licensed under a CC-BY license.

Immunohistochemistry-Paraffin: WDR73 Antibody [NBP1-82219]

Immunohistochemistry-Paraffin: WDR73 Antibody [NBP1-82219] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.