WFS1 Antibody (C8)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-42147
Key Product Details
Species Reactivity
Human
Applications
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # C8
Concentration
1 mg/ml
Product Specifications
Immunogen
Immunized with recombinant Human WFS1 (Uniprot#: O76024; Met1-Lys300 (Uniprot#: O76024)
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications for WFS1 Antibody (C8)
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
5-20ug/mL
Immunohistochemistry
5-20ug/mL
Western Blot
0.01-2ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: WFS1
WFS1 is the major component of Wolfram syndrome, a rare form of juvenile diabetes, also known as diabetes insipidus and mellitus with optic atrophy and deafness syndrome (DIDMOAD). WFS1 is normally up-regulated during insulin secretion, and inactivation of the protein causes ER stress. In turn, chronic ER stress is thought to play a major role in Wolfram syndrome.
Long Name
Wolfram Syndrome 1
Alternate Names
DFNA14, DFNA38, DFNA6, DIDMOAD, WFRS, Wolframin
Gene Symbol
WFS1
Additional WFS1 Products
Product Specific Notices for WFS1 Antibody (C8)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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