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WNK1 Antibody (26G7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26251

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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NBP3-26251-100ul
NBP3-26251-50ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunohistochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 26G7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for WNK1 Antibody (26G7)

Immunogen

A synthesized peptide derived from Human WNK1 [UniProt Q9H4A3]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for WNK1 Antibody (26G7)

WNK1 Antibody (26G7)

Immunohistochemistry: WNK1 Antibody (26G7) [NBP3-26251] -

Immunohistochemistry: WNK1 Antibody (26G7) [NBP3-26251] - Image of WNK1 Antibody diluted at 1:50 and staining in paraffin-embedded human brain tissue performed. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.60% DAB.
WNK1 Antibody (26G7)

Immunohistochemistry: WNK1 Antibody (26G7) [NBP3-26251] -

Immunohistochemistry: WNK1 Antibody (26G7) [NBP3-26251] - Image of WNK1 Antibody diluted at 1:50 and staining in paraffin-embedded human brain tissue performed. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.60% DAB.

Applications for WNK1 Antibody (26G7)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl and 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: WNK1

WNK lysine deficient protein kinase 1 (WNK1) is a cytoplasmic serine-threonine kinase expressed in the distal nephron which likely plays an important role in hypertension. WNK1 is responsible for controling Na+ and Cl- ion transport by inhibiting the activity of other related protein kinases, such as WNK4.

WNK1 mutations have been associated with Gordon hyperkalemia-hypertension syndrome (pseudohypoaldosteronism type II) and congenital sensory neuropathy.

WNK1 is also known as Human Accelerated Region 5, and is thought to have played a key role in differentiating humans from apes.

Long Name

WNK Lysine-deficient Protein Kinase 1

Alternate Names

KDP, PHA2C, PRKWNK1

Gene Symbol

WNK1

Additional WNK1 Products

Product Documents for WNK1 Antibody (26G7)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for WNK1 Antibody (26G7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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