WNK1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14518

Novus Biologicals, part of Bio-Techne
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NBP3-14518
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bat (100%), Equine (100%), Hamster (100%), Monkey (100%), Mouse (100%), Primate (100%), Rabbit (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

View all WNK1 Antibodies »

Product Specifications

Immunogen

Synthetic 17 amino acid peptide near C-Terminus of human WNK1.

Epitope

C-Terminus

Reactivity Notes

Expected reactivity based on percent sequence identity: Bovine (88%)

Specificity

Human WNK1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for WNK1 Antibody

Immunohistochemistry: WNK1 Antibody [NBP3-14518]

Immunohistochemistry: WNK1 Antibody [NBP3-14518]

Immunohistochemistry: WNK1 Antibody [NBP3-14518] - Immunohistochemistry of non-small cell carcinoma of the lung.
Immunohistochemistry-Paraffin: WNK1 Antibody [NBP3-14518]

Immunohistochemistry-Paraffin: WNK1 Antibody [NBP3-14518]

Immunohistochemistry-Paraffin: WNK1 Antibody [NBP3-14518] - Immunohistochemistry of formalin-fixed, paraffin-embedded human skeletal muscle after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: WNK1 Antibody [NBP3-14518]

Immunohistochemistry-Paraffin: WNK1 Antibody [NBP3-14518]

Immunohistochemistry-Paraffin: WNK1 Antibody [NBP3-14518] - Immunohistochemistry of formalin-fixed, paraffin-embedded human skin melanoma after heat-induced antigen retrieval.
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Applications for WNK1 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: WNK1

WNK lysine deficient protein kinase 1 (WNK1) is a cytoplasmic serine-threonine kinase expressed in the distal nephron which likely plays an important role in hypertension. WNK1 is responsible for controling Na+ and Cl- ion transport by inhibiting the activity of other related protein kinases, such as WNK4.

WNK1 mutations have been associated with Gordon hyperkalemia-hypertension syndrome (pseudohypoaldosteronism type II) and congenital sensory neuropathy.

WNK1 is also known as Human Accelerated Region 5, and is thought to have played a key role in differentiating humans from apes.

Long Name

WNK Lysine-deficient Protein Kinase 1

Alternate Names

KDP, PHA2C, PRKWNK1

Gene Symbol

WNK1

Additional WNK1 Products

Product Documents for WNK1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for WNK1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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