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Wnt-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14519

Novus Biologicals, part of Bio-Techne
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NBP3-14519

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Chicken (95%), Equine (100%), Hamster (95%), Monkey (100%), Mouse (100%), Porcine (100%), Primate (100%), Rabbit (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic 19 amino acid peptide from internal region of human Wnt-1.

Epitope

Internal

Specificity

Human Wnt-1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Wnt-1 Antibody

Immunohistochemistry-Paraffin: Wnt-1 Antibody [NBP3-14519]

Immunohistochemistry-Paraffin: Wnt-1 Antibody [NBP3-14519]

Immunohistochemistry-Paraffin: Wnt-1 Antibody [NBP3-14519] - Immunohistochemistry of formalin-fixed, paraffin-embedded human small intestine after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: Wnt-1 Antibody [NBP3-14519]

Immunohistochemistry-Paraffin: Wnt-1 Antibody [NBP3-14519]

Immunohistochemistry-Paraffin: Wnt-1 Antibody [NBP3-14519] - Immunohistochemistry of formalin-fixed, paraffin-embedded human kidney after heat-induced antigen retrieval.

Applications for Wnt-1 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Wnt-1

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. (provided by RefSeq)

Long Name

Wingless-type MMTV Integration Site Family, Member 1

Alternate Names

Int-1, Wnt1

Gene Symbol

WNT1

Additional Wnt-1 Products

Product Documents for Wnt-1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Wnt-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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