WWOX Antibody (SR2547)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27813

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27813
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2547

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all WWOX Antibodies »

Product Summary for WWOX Antibody (SR2547)

Immunogen

Recombinant protein of human WWOX (Uniprot #: Q9NZC7)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for WWOX Antibody (SR2547)

Immunohistochemistry-Paraffin: WWOX Antibody (SR2547) [NBP3-27813] -

Immunohistochemistry-Paraffin: WWOX Antibody (SR2547) [NBP3-27813] - Immunohistochemistry analysis of paraffin-embedded Human lung cancer. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western Blot: WWOX Antibody (SR2547) [NBP3-27813] -

Western Blot: WWOX Antibody (SR2547) [NBP3-27813] - Western blot analysis of WWOX in Hela, U2OS, U251MG lysates

Western Blot: WWOX Antibody (SR2547) [NBP3-27813] -

Western Blot: WWOX Antibody (SR2547) [NBP3-27813] - Western blot analysis of WWOX in mouse testis, mouse spleen lysates

Applications for WWOX Antibody (SR2547)

Application
Recommended Usage

Immunohistochemistry

1:50-1:100

Immunoprecipitation

1:20

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: WWOX

WW domain-containing oxidoreductase (WWOX) is a proapoptotic protein and a tumor suppressor gene. Because mutation or deletion in the coding region of WWOX is rarely found, it is speculated that the appearance of aberrant transcripts affects progression of many cancers. In addition, protein levels of WWOX, its Tyr33-phosphorylated form, and WOX2 are significantly down-regulated in the neurons of Alzheimer's hippocampi.

Long Name

WW Domain Containing Oxidoreductase

Alternate Names

FOR, FRA16D, SDR41C1, WOX1

Gene Symbol

WWOX

Additional WWOX Products

Product Documents for WWOX Antibody (SR2547)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for WWOX Antibody (SR2547)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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