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XAGE3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-31740

Novus Biologicals, part of Bio-Techne
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NBP2-31740
NBP2-31740-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SQSKTGGECGNGPDDQGKILPKSEQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for XAGE3 Antibody

Immunohistochemistry-Paraffin: XAGE3 Antibody [NBP2-31740]

Immunohistochemistry-Paraffin: XAGE3 Antibody [NBP2-31740]

Immunohistochemistry-Paraffin: XAGE3 Antibody [NBP2-31740] - Staining of human cerebral cortex shows strong nuclear positivity in neuronal cells.

Applications for XAGE3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: XAGE3

XAGE3 is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5' UTR. [provided by RefSeq]. Transcript Variant: This variant (1) has an alternate exon 1, as compared to variant 2. It thus has a different and longer 5' UTR, but encodes the same protein as variant 2.

Alternate Names

Cancer/testis antigen 12.3, cancer/testis antigen family 12, member 3a, cancer/testis antigen family 12, member 3b, CT12.3, CT12.3a, CT12.3b, G antigen family D member 4, G antigen, family D, 4, MGC71925, PLAC6GAGED4, placenta-specific 6, placenta-specific 6; G antigen, family D, 4, Placenta-specific gene 6 protein, pp9012, Protein XAGE-3, X antigen family, member 3, XAGE-3

Gene Symbol

XAGE3

UniProt

Additional XAGE3 Products

Product Documents for XAGE3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for XAGE3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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