XPC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38261

Novus Biologicals, part of Bio-Techne
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NBP2-38261
NBP2-38261-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all XPC Antibodies »

Product Summary for XPC Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: EEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNEDSNEEEEESENDW

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for XPC Antibody

Western Blot: XPC Antibody [NBP2-38261]

Western Blot: XPC Antibody [NBP2-38261]

Western Blot: XPC Antibody [NBP2-38261] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG
Immunocytochemistry/ Immunofluorescence: XPC Antibody [NBP2-38261]

Immunocytochemistry/ Immunofluorescence: XPC Antibody [NBP2-38261]

Immunocytochemistry/Immunofluorescence: XPC Antibody [NBP2-38261] - Immunofluorescent staining of human cell line MCF7 shows localization to nucleus. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: XPC Antibody [NBP2-38261]

Immunohistochemistry-Paraffin: XPC Antibody [NBP2-38261]

Immunohistochemistry-Paraffin: XPC Antibody [NBP2-38261] - Staining of human fallopian tube shows moderate to strong nuclear positivity in glandular cells.
View 3 more images

Applications for XPC Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: XPC

Human XPC (Xeroderma pigmentosum group C) is a member of a family of proteins that has been shown to be involved in the repair of DNA via the nucleotide excision repair (NER) pathway. Specifically, XPC is believed to be a part of a heteromeric protein complex that is involved in the recognition of the DNA lesions during global genomic repair but not transcription-coupled repair.

Alternate Names

complementation group C antibody, p125, RAD4, Xeroderma pigmentosum group C-complementing protein, xeroderma pigmentosum, complementation group C, XP3, XPCCDNA repair protein complementing XP-C cells

Gene Symbol

XPC

UniProt

Q01831 (Human)

Additional XPC Products

Product Documents for XPC Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for XPC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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