XPD Antibody (6T9K6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15704

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15704-100ul
NBP3-15704-20ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 6T9K6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all XPD Antibodies »

Product Summary for XPD Antibody (6T9K6)

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 600-700 of human XPD (P18074). ARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEH

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for XPD Antibody (6T9K6)

Western Blot: XPD Antibody (6T9K6) [NBP3-15704]

Western Blot: XPD Antibody (6T9K6) [NBP3-15704]

Western Blot: XPD Antibody (6T9K6) [NBP3-15704] - Western blot analysis of extracts of various cell lines, using XPD antibody (NBP3-15704) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Immunohistochemistry-Paraffin: XPD Antibody (6T9K6) [NBP3-15704]

Immunohistochemistry-Paraffin: XPD Antibody (6T9K6) [NBP3-15704]

Immunohistochemistry-Paraffin: XPD Antibody (6T9K6) [NBP3-15704] - Immunohistochemistry of paraffin-embedded mouse brain using XPD Rabbit mAb (NBP3-15704) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Immunohistochemistry-Paraffin: XPD Antibody (6T9K6) [NBP3-15704]

Immunohistochemistry-Paraffin: XPD Antibody (6T9K6) [NBP3-15704]

Immunohistochemistry-Paraffin: XPD Antibody (6T9K6) [NBP3-15704] - Immunohistochemistry of paraffin-embedded rat kidney using XPD Rabbit mAb (NBP3-15704) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
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Applications for XPD Antibody (6T9K6)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: XPD

The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

Xeroderma Pigmentosum D

Alternate Names

EM9, ERCC2

Gene Symbol

ERCC2

Additional XPD Products

Product Documents for XPD Antibody (6T9K6)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for XPD Antibody (6T9K6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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