XPD Antibody (S08-2I3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15112

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15112-100ul
NBP3-15112-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-2I3

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all XPD Antibodies »

Product Summary for XPD Antibody (S08-2I3)

Immunogen

A synthetic peptide of human XPD (Uniprot#: P18074)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

80 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for XPD Antibody (S08-2I3)

Western Blot: XPD Antibody (S08-2I3) [NBP3-15112]

Western Blot: XPD Antibody (S08-2I3) [NBP3-15112]

Western Blot: XPD Antibody (S08-2I3) [NBP3-15112] - Western blot detection of XPD in Jurkat, Hela cell lysates using XPD Rabbit mAb (1:500 diluted). Predicted band size: 87kDa. Observed band size: 80kDa.
Immunocytochemistry/ Immunofluorescence: XPD Antibody (S08-2I3) [NBP3-15112]

Immunocytochemistry/ Immunofluorescence: XPD Antibody (S08-2I3) [NBP3-15112]

Immunocytochemistry/Immunofluorescence: XPD Antibody (S08-2I3) [NBP3-15112] - Immunocytochemistry of XPD (green) in Hela using XPD Rabbit mAb at dilution 1/50, and DAPI (blue)

Applications for XPD Antibody (S08-2I3)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1/100

Western Blot

1/1000-1/5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: XPD

The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

Xeroderma Pigmentosum D

Alternate Names

EM9, ERCC2

Gene Symbol

ERCC2

Additional XPD Products

Product Documents for XPD Antibody (S08-2I3)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for XPD Antibody (S08-2I3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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