XRN2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-57539

Novus Biologicals, part of Bio-Techne
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NB100-57539
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human, Mouse

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all XRN2 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human 5'-3' exoribonuclease 2 using the numbering given in entry NP_036387.2 (GeneID 22803).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for XRN2 Antibody

Western Blot: XRN2 Antibody [NB100-57539]

Western Blot: XRN2 Antibody [NB100-57539]

Western Blot: XRN2 Antibody [NB100-57539] - Detection of human and mouse XRN2 by western blot. Samples: Whole cell lysate (50 ug) from HeLa, MCF-7, HEK293T, TCMK-1, and NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-XRN2 antibody NB100-57539 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Western Blot: XRN2 Antibody [NB100-57539]

Western Blot: XRN2 Antibody [NB100-57539]

Western Blot: XRN2 Antibody [NB100-57539] - Detection of Human and Mouse XRN2 on HeLa whole cell lysate using NB100-57539. XRN2 was immunoprecipitated by another rabbit anti-XRN2 antibodies and NB100-57541.

Applications for XRN2 Antibody

Application
Recommended Usage

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: XRN2

XRN2 is a 5'-to-3' exoribonuclease involved in 3'-end mRNA processing. XRN2 is important for transcription termination and is responsible for degrading the downstream 3'-end-cleaved RNA. Recent studies show that XRN2 is recruited to 3'-end processing machinery by p54nrb/PSF. Alternate names for XRN2 include 5'-3' exoribonuclease 2, DHM1-like protein, and DHP protein.

Alternate Names

5'-3' exoribonuclease 2, DHM1-like protein, Dhm1-like protein (mouse homolog), DHP protein, EC 3.1.13, EC 3.1.13.-

Entrez Gene IDs

22803 (Human)

Gene Symbol

XRN2

UniProt

NP_036387.2 (Human)

Additional XRN2 Products

Product Documents for XRN2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for XRN2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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