XYLT2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-62319

Novus Biologicals, part of Bio-Techne
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NBP1-62319
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all XYLT2 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to XYLT2(xylosyltransferase II) The peptide sequence was selected form the C terminal of XYLT2. Peptide sequence LRPGPWTVRLLQFWEPLGETRFLVLPLTFNRKLPLRKDDASWLHAGPPHN. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for XYLT2 Antibody

Western Blot: XYLT2 Antibody [NBP1-62319]

Western Blot: XYLT2 Antibody [NBP1-62319]

Western Blot: XYLT2 Antibody [NBP1-62319] - Human Muscle lysate, concentration 0.2-1 ug/ml.

Applications for XYLT2 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: XYLT2

XYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alternate Names

EC 2.4.2.26, Peptide O-xylosyltransferase 1, PXYLT2, XT2UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase, xylosyltransferase 2, xylosyltransferase IIXT-IIprotein xylosyltransferase 2, XylT-II

Gene Symbol

XYLT2

OMIM

NP_071450 (Human)

UniProt

Q9H1B5 (Human)

Additional XYLT2 Products

Product Documents for XYLT2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for XYLT2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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