YME1L1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49499

Novus Biologicals, part of Bio-Techne
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NBP2-49499
NBP2-49499-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all YME1L1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: AVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for YME1L1 Antibody

Immunocytochemistry/ Immunofluorescence: YME1L1 Antibody [NBP2-49499]

Immunocytochemistry/ Immunofluorescence: YME1L1 Antibody [NBP2-49499]

Immunocytochemistry/Immunofluorescence: YME1L1 Antibody [NBP2-49499] - Staining of human cell line U-2 OS shows localization to nuclear bodies & mitochondria.
Immunohistochemistry-Paraffin: YME1L1 Antibody [NBP2-49499]

Immunohistochemistry-Paraffin: YME1L1 Antibody [NBP2-49499]

Immunohistochemistry-Paraffin: YME1L1 Antibody [NBP2-49499] - Staining of human heart muscle shows moderate cytoplasmic positivity in myocytes.

Applications for YME1L1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: YME1L1

The protein encoded by the YME1L1 gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

ATP-dependent metalloprotease FtsH1, ATP-dependent metalloprotease FtsH1 homolog, ATP-dependent metalloprotease YME1L1, EC 3.4.24, EC 3.4.24.-, FTSH, FTSH1, MEG4, Meg-4, PAMPATP-dependent zinc metalloprotease YME1L1, Presenilin-associated metalloprotease, YME1 (S.cerevisiae)-like 1, YME1-like 1 (S. cerevisiae), YME1-like protein 1, YME1Lmeg-4

Gene Symbol

YME1L1

Additional YME1L1 Products

Product Documents for YME1L1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for YME1L1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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