ZDHHC17 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1505

Novus Biologicals, part of Bio-Techne
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NB100-1505
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Canine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all ZDHHC17 Antibodies »

Product Specifications

Immunogen

Peptide with sequence CYDQISGSGYQLV corresponding to C-Terminus according to NP_056151.2.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for ZDHHC17 Antibody

Western Blot: ZDHHC17 Antibody [NB100-1505]

Western Blot: ZDHHC17 Antibody [NB100-1505]

Western Blot: ZDHHC17 Antibody [NB100-1505] - (1ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: ZDHHC17 Antibody [NB100-1505]

Immunohistochemistry-Paraffin: ZDHHC17 Antibody [NB100-1505]

Immunohistochemistry-Paraffin: ZDHHC17 Antibody [NB100-1505] - staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for ZDHHC17 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 ug/ml

Peptide ELISA

Detection limit 1:8000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 70 kDa band observed in human and mouse brain lysates (calculated MW of 72.7 kDa band according to NP_056151.1).
IHC: Paraffin embedded Human Testis.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ZDHHC17

ZDHHC17 / HIP14 is a neuronal palmitoyl transferase. Palmitoylation is critical for trafficking and function of signaling molecules, neurotransmitter receptors, and synaptic scaffolding proteins in neurons. ZDHHC17 also causes cellular transformation. It has been shown that mRNA encoding ZDHHC17 is up-regulated in a number of types of human tumors, thus ZDHHC17 and other PATs (palmitoyl acyltransferases) are potential targets for new anticancer drugs.

Alternate Names

DHHC-17, EC 2.3.1, EC 2.3.1.-, HIP14HIP-14, huntingtin interacting protein 14, huntingtin interacting protein 3, Huntingtin interacting protein H, Huntingtin yeast partner H, Huntingtin-interacting protein 14, Huntingtin-interacting protein 3, Huntingtin-interacting protein H, HYPHHIP-3, KIAA0946HIP3, palmitoyltransferase ZDHHC17, Putative MAPK-activating protein PM11, Putative NF-kappa-B-activating protein 205, Zinc finger DHHC domain-containing protein 17, zinc finger, DHHC domain containing 17, zinc finger, DHHC-type containing 17

Entrez Gene IDs

23390 (Human)

Gene Symbol

ZDHHC17

UniProt

NP_056151. (Human)

Additional ZDHHC17 Products

Product Documents for ZDHHC17 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ZDHHC17 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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