Zeta Opioid Receptor Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90340

Novus Biologicals, part of Bio-Techne
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NBP1-90340
NBP1-90340-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Zeta Opioid Receptor Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Zeta Opioid Receptor Antibody

Immunocytochemistry/ Immunofluorescence: Zeta Opioid Receptor Antibody [NBP1-90340]

Immunocytochemistry/ Immunofluorescence: Zeta Opioid Receptor Antibody [NBP1-90340]

Immunocytochemistry/Immunofluorescence: Zeta Opioid Receptor Antibody [NBP1-90340] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: Zeta Opioid Receptor Antibody [NBP1-90340]

Immunohistochemistry-Paraffin: Zeta Opioid Receptor Antibody [NBP1-90340]

Immunohistochemistry-Paraffin: Zeta Opioid Receptor Antibody [NBP1-90340] - Staining in human spleen and skeletal muscle tissues using anti-OGFR antibody. Corresponding OGFR RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Zeta Opioid Receptor Antibody [NBP1-90340]

Immunohistochemistry-Paraffin: Zeta Opioid Receptor Antibody [NBP1-90340]

Immunohistochemistry-Paraffin: Zeta Opioid Receptor Antibody [NBP1-90340] - Staining of human liver shows nuclear positivity in hepatocytes.
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Applications for Zeta Opioid Receptor Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Zeta Opioid Receptor

Zeta Opioid Receptor is the receptor for opioid growth factor (OGF), also known as Met-enkephalin. Met-enkephalin (met-Enk) is an opioid peptide that acts via three main subtypes of receptors referred to as mu, delta and zeta receptors. The first two receptor subtypes mediate the classic opioid effects of met-Enk, wheras zeta-receptors are reported to be involved in the non-opioid actions of the peptide. OGF (Met-enkephalin)is an inhibitory peptide that modulates cell proliferation and tissue organization during development, cellular renewal, cancer, wound healing, and angiogenesis. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. It has been found that the progression of some tumours is associated with the down regulation of opioid growth factor receptor expression.

Alternate Names

7-60, 7-60 protein, OGFr, opioid growth factor receptor, Protein 7-60, Zeta-type opioid receptor

Entrez Gene IDs

11054 (Human)

Gene Symbol

OGFR

UniProt

Q9NZT2 (Human)

Additional Zeta Opioid Receptor Products

Product Documents for Zeta Opioid Receptor Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Zeta Opioid Receptor Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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