Zeta Opioid Receptor Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-97488

Novus Biologicals, part of Bio-Techne
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NBP2-97488-100ul
NBP2-97488-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Zeta Opioid Receptor Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with E. coli-derived Human Zeta Opioid Receptor fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Zeta Opioid Receptor Antibody

Immunocytochemistry/ Immunofluorescence: Zeta Opioid Receptor Antibody [NBP2-97488]

Immunocytochemistry/ Immunofluorescence: Zeta Opioid Receptor Antibody [NBP2-97488]

Immunocytochemistry/Immunofluorescence: Zeta Opioid Receptor Antibody [NBP2-97488] - Immunofluorescence staining of Zeta Opioid Receptor in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human Zeta Opioid Receptor polyclonal antibody (dilution ratio 1:200) at 4C overnight. Then cells were stained with the Alexa Fluor(R)488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus .

Applications for Zeta Opioid Receptor Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:500

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Zeta Opioid Receptor

Zeta Opioid Receptor is the receptor for opioid growth factor (OGF), also known as Met-enkephalin. Met-enkephalin (met-Enk) is an opioid peptide that acts via three main subtypes of receptors referred to as mu, delta and zeta receptors. The first two receptor subtypes mediate the classic opioid effects of met-Enk, wheras zeta-receptors are reported to be involved in the non-opioid actions of the peptide. OGF (Met-enkephalin)is an inhibitory peptide that modulates cell proliferation and tissue organization during development, cellular renewal, cancer, wound healing, and angiogenesis. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. It has been found that the progression of some tumours is associated with the down regulation of opioid growth factor receptor expression.

Alternate Names

7-60, 7-60 protein, OGFr, opioid growth factor receptor, Protein 7-60, Zeta-type opioid receptor

Gene Symbol

OGFR

Additional Zeta Opioid Receptor Products

Product Documents for Zeta Opioid Receptor Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Zeta Opioid Receptor Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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