ZFYVE9 Antibody (SR1275)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22552

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22552-100ul
NBP3-22552-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1275

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ZFYVE9 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human ZFYVE9 (Uniprot #: O95405)

Specificity

Detects endogenous levels of total ZFYVE9

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

180 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ZFYVE9 Antibody (SR1275)

Western Blot: ZFYVE9 Antibody (SR1275) [NBP3-22552] -

Western Blot: ZFYVE9 Antibody (SR1275) [NBP3-22552] - Western blot analysis using NBP3-22552 in A673 cell lysate.

Applications for ZFYVE9 Antibody (SR1275)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ZFYVE9

ZFYVE9 encodes a double zinc finger (FYVE domain) protein that interacts directly with SMAD2 and SMAD3, and is involved in Alzheimer's disease. SMAD proteins transmit signals from transmembrane serine/threonine kinase receptors to the nucleus. The FYVE domain has been identified in a number of unrelated signaling molecules. This protein functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE domain is required to maintain the normal localization of this protein but is not involved in mediating interaction with SMADs. The C-terminal domain of this protein interacts with the TGFB receptor. This protein is a component of the TGFB pathway that brings the SMAD substrate to the receptor. Three alternatively spliced transcripts encoding distinct isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

Madh-interacting protein, MADHIP, mothers against decapentaplegic homolog interacting protein, mothers against decapentaplegic homolog interacting protein, receptoractivation anchor, NSP, receptor activation anchor, SARAhSARA, Smad anchor for receptor activation, SMADIPMAD, mothers against decapentaplegic homolog (Drosophila) interacting protein, zinc finger FYVE domain-containing protein 9, zinc finger, FYVE domain containing 9

Gene Symbol

ZFYVE9

Additional ZFYVE9 Products

Product Documents for ZFYVE9 Antibody (SR1275)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ZFYVE9 Antibody (SR1275)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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