Zic2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24607

Novus Biologicals, part of Bio-Techne
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NBP2-24607
NBP2-24607SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Bovine, Canine, Chicken, Equine, Primate

Predicted:

Monkey (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Zic2 Antibodies »

Product Summary for Zic2 Antibody

Immunogen

A portion of amino acid 350 to 400 of human ZIC2 was used as immunogen.

Reactivity Notes

The amino acid sequence used as immunogen is 88% homologous in Xenopus and Chicken.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Zic2 Antibody

Western Blot: Zic2 Antibody [NBP2-24607]

Western Blot: Zic2 Antibody [NBP2-24607]

Western Blot: Zic2 Antibody [NBP2-24607] - Analysis of ZIC2 in HepG2 cell lysate using 1) pre-bleed, and 2) this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Applications for Zic2 Antibody

Application
Recommended Usage

Western Blot

4-7 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Zic2

ZIC2 (zinc finger protein of the cerebellum 2) is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.

Alternate Names

HPE5Zic family member 2 (odd-paired Drosophila homolog), Zic family member 2 (odd-paired homolog, Drosophila), Zinc finger protein of the cerebellum 2, zinc finger protein ZIC 2

Gene Symbol

ZIC2

UniProt

O95409 (Human)

Additional Zic2 Products

Product Documents for Zic2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Zic2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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