ZMPSTE24 Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84755
Key Product Details
Species Reactivity
Validated:
Human
Predicted:
Rat (94%). Backed by our 100% Guarantee.
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Summary for ZMPSTE24 Antibody
Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: KTTTHVPPELGQIMDSETFEKSRLYQLDKSTFS
Reactivity Notes
Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%)
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for ZMPSTE24 Antibody
![Western Blot: ZMPSTE24 Antibody [NBP1-84755]](https://resources.bio-techne.com/images/products/ZMPSTE24-Antibody-Western-Blot-NBP1-84755-img0006.jpg "Western Blot: ZMPSTE24 Antibody [NBP1-84755]")
Western Blot: ZMPSTE24 Antibody [NBP1-84755]
Western Blot: ZMPSTE24 Antibody [NBP1-84755] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted)![Immunohistochemistry-Paraffin: ZMPSTE24 Antibody [NBP1-84755]](https://resources.bio-techne.com/images/products/ZMPSTE24-Antibody-Immunohistochemistry-Paraffin-NBP1-84755-img0002.jpg "Immunohistochemistry-Paraffin: ZMPSTE24 Antibody [NBP1-84755]")
Immunohistochemistry-Paraffin: ZMPSTE24 Antibody [NBP1-84755]
Immunohistochemistry-Paraffin: ZMPSTE24 Antibody [NBP1-84755] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells.Applications for ZMPSTE24 Antibody
Application
Recommended Usage
Immunohistochemistry
1:20 - 1:50
Immunohistochemistry-Paraffin
1:20 - 1:50
Western Blot
0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Immunogen affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: ZMPSTE24
FACE-1 is widely expressed, with the highest levels found in the kidney, prostate, testis and ovary.
Mutations in ZMPSTE24 have been associated with human diseases such as mandibuloacral dysplasia with type B lipodystrophy (MADB) and lethal tight skin contracture syndrome (LTSCS), often due to the accumulation of LMNA precursors. It is theorized that ZMPSTE24 may play an important role in human ageing, based on its association with LMNA.
Alternate Names
zona pellucida binding protein 2, zona pellucida-binding protein 2, ZPBP-like protein, ZPBPLMGC41930
Gene Symbol
ZMPSTE24
Additional ZMPSTE24 Products
Product Documents for ZMPSTE24 Antibody
Product Specific Notices for ZMPSTE24 Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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